Case ID: 12-001
Web Published: Mar 01, 2011
Available for: Non-exclusive licenses.
We have developed a novel fluorescent assay for the screening of small molecules targeting dengue virus.
Our technology is based on stable cell lines expressing a replicon of dengue virus, optimised for assessing drug efficacy in vitro through incorporation of a fluorescent reporter element.
Dengue hemorrhagic fever is a flavivirus with the major disease burden occurring in South East Asia, the Americas and the Western Pacific, but recent cases have been reported in Florida. It is possible that environmental warming may see increased distribution of dengue cases.
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